Obesity, cancer and metabolic disease

Lifestyle-related diseases such as obesity, cancer and metabolic diseases represent a grand challenge to health and wellbeing globally. These complex disorders are difficult to treat effectively, and are increasingly prevalent as sedentary lifestyles and calorie-rich, nutrient-poor diets cause an obesity crisis throughout the developed world. Our research focuses on the relationship between the food we eat and the risk of obesity and chronic diseases such as non-alcoholic fatty liver, cardiovascular disease and cancer.

Our research applies a variety of modern molecular, cellular biology techniques including high-throughput approaches to transcriptomics, proteomics and metabolomics to study the mechanisms by which nutrients affect cell function and metabolism at the organ, cellular and molecular levels. We investigate nutrient-disease interactions at the cellular level with the aim of exploring and understanding the links between diet and disease, and developing strategies that will help ensure healthier and more nutritious food for all.

Specific areas of research interest include: the role of dietary antioxidants in the prevention of oxidative stress and inflammation related diseases such as obesity, diabetes and cardiovascular diseases; how cancer cell biology can be manipulated by components derived from and modulated by the diet; biomarkers of nutrient status, health and disease; and how dietary nutrients influence the development and progression of obesity and non-alcoholic fatty liver disease.

Research team

If you are interested in collaborating with us or joining our research team, please get in touch. View all members of the obesity, cancer and metabolic disease theme.

PhD projects

We have opportunities for prospective PhD students. Potential projects can be found in our postgraduate research opportunities directory.