Helping the anti-parasitic medicine go down
Scientists have developed a new way to deliver anti-parasitic medicines more efficiently.
An international team, led by Professor Francisco Goycoolea from the School of Food Science and Nutrition and Dr Claudio Salomon from the Universidad Nacional de Rosario, Argentina, and in collaboration with colleagues at the University of Münster, Germany, have developed a novel pharmaceutical formulation to administer triclabendazole – an anti-parasitic drug used to treat a type of flatworm infection – in billions of tiny capsules.
The World Health Organisation estimates that 2.4 million people are infected with fascioliasis, the disease caused by flatworms and treated with triclabendazole.
Anti-parasitic drugs do not become effective until they dissolve and are absorbed. Traditionally, these medicines are highly insoluble and this limits their therapeutic effect.
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