Dr Lorna Dougan

Profile

We are developing biophysical approaches for characterising the physical mechanisms of protein’s which survive in extreme environments. By examining single molecules one at a time, the individual dynamics of sub-populations can be measured. This approach could aid in the design of molecules for exploitation in biotechnology.

Astbury Centre for Structural and Molecular Biology

Institute of Physics Liquids and Complex Fluids Group

Institute of Physics Yorkshire Branch

Research interests

Our group is interested in using novel biophysical approaches to explore the structure and dynamics of molecules in aqueous solutions. The major theme of our multidisciplinary program involves the development of single molecule manipulation techniques as well as structural studies using neutron diffraction and computational modelling. These powerful techniques are used as tools to study biomolecular self-assembly in both simple and complex systems.

Our current areas of interest include:
- The development of instrumentation for the mechanical manipulation of single molecules
- Understanding the action of cryoprotectant molecules
- Hydrogen bonding, percolation and micro-segregation in aqueous solutions
- Protein folding, stability and dynamics under extreme environmental conditions
- The development of enabling tools and technology for synthetic biology
- The design and characterisation of artificial biological levers for molecular motors
- The self-assembly and aggregation of disease relevant peptides and proteins

You can read more about our research on the Dougan Group web site!
 

Postgraduate research opportunities

We welcome enquiries from motivated and qualified applicants from all around the world who are interested in PhD study. Our research opportunities allow you to search for projects and scholarships.