Dr Peter Adams

Profile

Peter Adams is currently at the University of Leeds, UK, undertaking a University Academic Fellowship and funded by a BBSRC Future Leader Fellowship. He obtained a BSc in Biochemistry and Microbiology at University of Sheffield, UK (2004-2007), where undergraduate lectures sparked an interest in membrane proteins and energy-transducing membranes. He went on to study for a PhD at University of Sheffield (2007-2011) researching the membranes involved in “light harvesting” in photosynthetic bacteria, using atomic force microscopy and biochemical/ biophysical techniques.

Broadening his scientific horizons, he then took up a Postdoctoral Research Scholar position at Los Alamos National Laboratory, USA (2012-2014). There he gained insight into biomimetic systems, investigating supported lipid bilayers, lipopolysaccharide and polymer/dye-based artificial photosynthesis. Subsequently, he joined the Molecular and Nanoscale Physics group at the University of Leeds (2015-current), where he is undertaking research into bio-inspired model photosynthetic membranes.

Research interests

All biological cells, from bacteria to human epithelia, are surrounded by membranes comprised of lipids, proteins and other molecules. Biological cell membranes rely upon complex, hierarchical organization to elicit functional responses. To achieve specialized function some membranes form organized domains of protein proteins and multilamellar stacked arrangements, such as those found in the certain membranes involved in photosynthesis ('light-harvesting' membranes).

My research aims to develop new artificial 3-D-organized stacked membranes inspired by chloroplast thylakoids. We take a multi-disciplinary approach combining aspects of surface chemistry, nano/micro fabrication, protein biochemistry, spectroscopy and various microscopies to fully explore these membranes. Synthetic biology often uses genetic engineering or de novo chemical synthesis to develop minimal and/or modular systems of DNA, peptide sequences or organic molecules than can perform novel functions. My research uses purified LH proteins and natural lipids as building blocks to generate novel semi-synthetic systems. Long term goals include: (i) to mimic the natural stacked membrane systems to provide a controlled platform for understanding the assembly and biophysical properties of the membrane protein/lipids, (ii) to design new 3-D patterns of membranes onto solid surfaces with preservation of biological functionality, (iii) to build new bio/hybrid photonic devices. These controlled model membranes will act as a platform to test the factors influencing self-assembly, organisation and function in biological membranes, over multiple scales.

Various techniques are used to fully characterize the proteins, membranes and new devices from the micro- to the nanoscale. These include atomic force microscopy, electron microscopy fluorescence microscopy, spectroscopy, DLS, QCM, etc. We are always looking towards the latest, state-of-the-art technologies to enable the next breakthrough. Success in these efforts will represent a major advance in the controlled design of 3-D complex, functional biomaterials.

Qualifications

  • PhD, Biochemistry and Microbiology
  • BSc (Hons.) First Class, Biochemistry and Microbiology

Professional memberships

  • Institute of Physics
  • International Society of Photosynthesis Research
  • British Biophysical Society
  • Biophysical Society (USA)

Research groups and institutes

  • Molecular and Nanoscale Physics

Postgraduate research opportunities

We welcome enquiries from motivated and qualified applicants from all around the world who are interested in PhD study. Our research opportunities allow you to search for projects and scholarships.

Projects currently available: